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CD3ε is a 20 kD transmembrane protein and is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 plays a critical role in TCR signal transduction, T cell a
Learn moreCD28 (Cluster of Differentiation 28) is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is composed of a single Ig V-like extracellular domain, a transmembrane domain and an int
Learn moreInterferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons. It is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and
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The InVivoPro Anti-Mouse PD-1(CD279) in vivo antibody, Clone 29F.1A12, has emerged as a cornerstone in preclinical immunotherapy research. Developed by BioXCell, this highly specialized monoclonal antibody targets murine PD-1, a key immune checkpoint
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The InVivoPro Anti-Mouse CD8α in vivo antibody, Clone 2.43 has become a cornerstone in preclinical immunology research, offering researchers a precise and reliable tool to manipulate and study CD8⁺ T cells, the key cytotoxic effectors of the adaptive imm
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The InVivoPro Anti-Mouse Ly6G in vivo antibody, Clone 1A8 has emerged as a crucial asset in preclinical research, offering a powerful means to study and manipulate neutrophil functions in various disease models. Ly6G, a cell surface antigen highly express
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InvivoCrown, founded in 2021 in the Cambridge Science Park, UK, as a deep participant in immunology research, takes "Crowning Science" as its core philosophy and focuses on providing global researchers in the fields of immunology and oncology with high-purity, cost-effective, function-oriented in vivo-grade antibody solutions. Our team integrates cutting-edge technologies with pragmatist concepts. Led by a team of immunology experts from the University of Cambridge and with nearly 20 years of experience in antibody drug development, we have created a product matrix with both excellent performance and cost advantages – from classic immune checkpoint targets (such as PD1/PD-L1) to novel tumo
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