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BioSIM anti-Human Amyloid Beta/Aβ Antibody (Solanezumab Biosimilar), Research Grade

Catalog: SIM0781
Cost advantage to: SIM0047
Product Details Specifications Application References Related Products

Product Details

This non-therapeutic biosimilar shares Solanezumab’s variable regions (ideal for research). Solanezumab, a humanized IgG1κ anti-human APP antibody, binds soluble Aβ monomers (not aggregates), recognizes human Aβ’s 16-26 epitope, and reacts with truncated Aβ. Aβ relates to Alzheimer’s; preclinical studies show this antibody promotes brain Aβ clearance.
 

Specifications

Product Name BioSIM anti-Human Amyloid Beta/Aβ Antibody (Solanezumab Biosimilar), Research Grade
Size 1mg/5mg
Isotype /
Target Amyloid Beta/Aβ
Other Names LY2062430, CAS: 955085-14-0
CAS 955085-14-0
Reactivity Human
Host Species Humanized
Background This non-therapeutic biosimilar shares Solanezumab’s variable regions (ideal for research). Solanezumab, a humanized IgG1κ anti-human APP antibody, binds soluble Aβ monomers (not aggregates), recognizes human Aβ’s 16-26 epitope, and reacts with truncated Aβ. Aβ relates to Alzheimer’s; preclinical studies show this antibody promotes brain Aβ clearance.
Applications ELISA, FACS, Functional assay, Research in vivo
Purification Protein A/G
Storage To ensure appropriate storage, Please avoid repeated freeze thaw cycles. Keep the product at 4°C for short-term needs (1–2 weeks); Store at -20°C for up to 12 months.  For long-term storage, store at -80°C.
Shipping 2-8°C with blue ice
Concentration Lot specific, generally ≥ 5.0 mg/ml
Shelf Life 12 months from the date of receipt if stored as recommended
Formulation PBS, pH 7.4, contains no stabilizers or preservatives
Sterility 0.2 μM filtered
Endotoxin ≤ 1.0 EU/mg
Purity 99%

Application References

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