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BiosimilarsInvestigate biological therapeutic mechanisms with cost-effective, research-grade biosimilar antibodies.
This non-therapeutic biosimilar antibody, using the same variable regions as therapeutic Tanezumab, is ideal for research. It reacts with human nerve growth factor (NGF) — a neurotrophic factor regulating certain neurons’ growth, maintenance, proliferation and survival. NGF is essential for PNS neurons’ development, CNS cholinergic neurons’ functional integrity. Tanezumab, targeting NGF, treats pain via a novel mechanism different from conventional painkillers.
| Product Name | BioSIM anti-Human NGF/bNGF Antibody (Tanezumab Biosimilar), Research Grade |
| Size | 1mg/5mg |
| Isotype | IgG2-kappa |
| Target | NGF/bNGF |
| Other Names | PF-04383119, RN624, CAS: 880266-57-9 |
| CAS | 880266-57-9 |
| Reactivity | Human |
| Host Species | Humanized |
| Background | This non-therapeutic biosimilar antibody, using the same variable regions as therapeutic Tanezumab, is ideal for research. It reacts with human nerve growth factor (NGF) — a neurotrophic factor regulating certain neurons’ growth, maintenance, proliferation and survival. NGF is essential for PNS neurons’ development, CNS cholinergic neurons’ functional integrity. Tanezumab, targeting NGF, treats pain via a novel mechanism different from conventional painkillers. |
| Applications | ELISA, FACS, Functional assay, Research in vivo |
| Purification | Protein A/G |
| Storage | To ensure appropriate storage, Please avoid repeated freeze thaw cycles. Keep the product at 4°C for short-term needs (1–2 weeks); Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Shipping | 2-8°C with blue ice |
| Concentration | Lot specific, generally ≥ 5.0 mg/ml |
| Shelf Life | 12 months from the date of receipt if stored as recommended |
| Formulation | PBS, pH 7.4, contains no stabilizers or preservatives |
| Sterility | 0.2 μM filtered |
| Endotoxin | ≤ 1.0 EU/mg |
| Purity | 99% |
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