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This non-therapeutic biosimilar antibody shares variable regions with therapeutic Emapalumab, ideal for research. Emapalumab (fully human IgG1 mAb) binds free/receptor-bound IFNγ (20 kDa type II interferon, made by activated lymphocytes) to block IFNγ-receptor interaction. IFNγ has immunoregulatory/anti-proliferative/anti-viral/proinflammatory activities, modulates immune cells, signals via CD119/AF-1 heterodimer receptor (ubiquitous except mature erythrocytes).
| Product Name | BioSIM anti-Human IFNγ Antibody (Emapalumab Biosimilar), Research Grade |
| Size | 1mg/5mg |
| Isotype | IgG1-lambda |
| Target | IFNγ |
| Other Names | NI-0501, emapalumab-lzsg, CAS: 1709815-23-5 |
| CAS | 1709815-23-5 |
| Reactivity | Human |
| Host Species | Human |
| Background | This non-therapeutic biosimilar antibody shares variable regions with therapeutic Emapalumab, ideal for research. Emapalumab (fully human IgG1 mAb) binds free/receptor-bound IFNγ (20 kDa type II interferon, made by activated lymphocytes) to block IFNγ-receptor interaction. IFNγ has immunoregulatory/anti-proliferative/anti-viral/proinflammatory activities, modulates immune cells, signals via CD119/AF-1 heterodimer receptor (ubiquitous except mature erythrocytes). |
| Applications | ELISA, FACS, Functional assay, Research in vivo |
| Purification | Protein A/G |
| Storage | To ensure appropriate storage, Please avoid repeated freeze thaw cycles. Keep the product at 4°C for short-term needs (1–2 weeks); Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Shipping | 2-8°C with blue ice |
| Concentration | Lot specific, generally ≥ 5.0 mg/ml |
| Shelf Life | 12 months from the date of receipt if stored as recommended |
| Formulation | PBS, pH 7.4, contains no stabilizers or preservatives |
| Sterility | 0.2 μM filtered |
| Endotoxin | ≤ 1.0 EU/mg |
| Purity | 99% |
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