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Precisely identify antibody-specific signals using matched isotype controls optimised for in vivo experimentation.
BiosimilarsInvestigate biological therapeutic mechanisms with cost-effective, research-grade biosimilar antibodies.
This non-therapeutic biosimilar shares the same variable regions as therapeutic mirvetuximab (a chimeric human IgG1 mAb targeting FOLR1), ideal for research. FOLR1, a folate transport receptor, supports genome integrity, cell proliferation and signaling. More prevalent in epithelial cancers (e.g., ovarian), it’s a key anti-cancer target. The biosimilar is unconjugated, with high specificity and affinity for human FOLR1.
| Product Name | BioSIM anti-Human FOLR1/FRA Antibody (Mirvetuximab Biosimilar), Research Grade |
| Size | 1mg/5mg |
| Isotype | IgG1-kappa |
| Target | FOLR1/FRA |
| Other Names | M9346A, IMGN853, M9346A-sulfo-SPDB-DM4, CAS: 1453084-36-0 |
| CAS | 1453084-36-0 |
| Reactivity | Human |
| Host Species | Chimeric |
| Background | This non-therapeutic biosimilar shares the same variable regions as therapeutic mirvetuximab (a chimeric human IgG1 mAb targeting FOLR1), ideal for research. FOLR1, a folate transport receptor, supports genome integrity, cell proliferation and signaling. More prevalent in epithelial cancers (e.g., ovarian), it’s a key anti-cancer target. The biosimilar is unconjugated, with high specificity and affinity for human FOLR1. |
| Applications | ELISA, FACS, Functional assay, Research in vivo |
| Purification | Protein A/G |
| Storage | To ensure appropriate storage, Please avoid repeated freeze thaw cycles. Keep the product at 4°C for short-term needs (1–2 weeks); Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Shipping | 2-8°C with blue ice |
| Concentration | Lot specific, generally ≥ 5.0 mg/ml |
| Shelf Life | 12 months from the date of receipt if stored as recommended |
| Formulation | PBS, pH 7.4, contains no stabilizers or preservatives |
| Sterility | 0.2 μM filtered |
| Endotoxin | ≤ 1.0 EU/mg |
| Purity | 99% |
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