Discover our extensive collection of research-grade antibodies,
rigorously validated for in vivo applications.
Precisely identify antibody-specific signals using matched isotype controls optimised for in vivo experimentation.
BiosimilarsInvestigate biological therapeutic mechanisms with cost-effective, research-grade biosimilar antibodies.
This non-therapeutic biosimilar has the same variable regions as therapeutic antibody Tilvestamab, ideal for research. Tilvestamab targets AXL (a TAM family receptor) – overexpressed in cancers like renal cell carcinoma, NSCLC, and linked to tumor progression. It binds AXL’s extracellular domain, blocks Gas6 interaction and downstream pathways (PI3K/AKT, MAPK/ERK), suppressing tumor cell functions. Preclinically effective, it aids studying AXL signaling, tumor biology and AXL-targeted therapies.
| Product Name | BioSIM anti-Human AXL/UFO Antibody (Tilvestamab Biosimilar), Research Grade |
| Size | 1mg/5mg |
| Isotype | IgG1-kappa |
| Target | AXL/UFO |
| Other Names | Ab-2, BGB-149, CAS: 2226775-26-2 |
| CAS | 2226775-26-2 |
| Reactivity | Human |
| Host Species | Humanized |
| Background | This non-therapeutic biosimilar has the same variable regions as therapeutic antibody Tilvestamab, ideal for research. Tilvestamab targets AXL (a TAM family receptor) – overexpressed in cancers like renal cell carcinoma, NSCLC, and linked to tumor progression. It binds AXL’s extracellular domain, blocks Gas6 interaction and downstream pathways (PI3K/AKT, MAPK/ERK), suppressing tumor cell functions. Preclinically effective, it aids studying AXL signaling, tumor biology and AXL-targeted therapies. |
| Applications | ELISA, FACS, Functional assay, Research in vivo |
| Purification | Protein A/G |
| Storage | To ensure appropriate storage, Please avoid repeated freeze thaw cycles. Keep the product at 4°C for short-term needs (1–2 weeks); Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Shipping | 2-8°C with blue ice |
| Concentration | Lot specific, generally ≥ 5.0 mg/ml |
| Shelf Life | 12 months from the date of receipt if stored as recommended |
| Formulation | PBS, pH 7.4, contains no stabilizers or preservatives |
| Sterility | 0.2 μM filtered |
| Endotoxin | ≤ 1.0 EU/mg |
| Purity | 99% |
© 2021-2025 InvivoCrown Limited. All rights reserved.