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BiosimilarsInvestigate biological therapeutic mechanisms with cost-effective, research-grade biosimilar antibodies.
This biosimilar antibody shares the same variable regions as therapeutic Edrecolomab, ideal for research. Edrecolomab, a murine monoclonal antibody, binds tumor-associated EpCAM (CD326/17-1A) — a 40-42 kDa transmembrane glycoprotein on epithelial cells, some immune cells, and carcinomas (e.g., colon, breast). EpCAM mediates cell adhesion and may act as a growth factor receptor. Edrecolomab binds it to recruit immune effector cells for antitumor cytotoxicity.
| Product Name | BioSIM anti-Human EpCAM/CD326 Antibody (Edrecolomab Biosimilar), Research Grade |
| Size | 1mg/5mg |
| Isotype | IgG2a-kappa |
| Target | EpCAM/CD326 |
| Other Names | 17-1A, CAS: 156586-89-9 |
| CAS | 156586-89-9 |
| Reactivity | Human |
| Host Species | Mouse |
| Background | This biosimilar antibody shares the same variable regions as therapeutic Edrecolomab, ideal for research. Edrecolomab, a murine monoclonal antibody, binds tumor-associated EpCAM (CD326/17-1A) — a 40-42 kDa transmembrane glycoprotein on epithelial cells, some immune cells, and carcinomas (e.g., colon, breast). EpCAM mediates cell adhesion and may act as a growth factor receptor. Edrecolomab binds it to recruit immune effector cells for antitumor cytotoxicity. |
| Applications | ELISA, FACS, Functional assay, Research in vivo |
| Purification | Protein A/G |
| Storage | To ensure appropriate storage, Please avoid repeated freeze thaw cycles. Keep the product at 4°C for short-term needs (1–2 weeks); Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Shipping | 2-8°C with blue ice |
| Concentration | Lot specific, generally ≥ 5.0 mg/ml |
| Shelf Life | 12 months from the date of receipt if stored as recommended |
| Formulation | PBS, pH 7.4, contains no stabilizers or preservatives |
| Sterility | 0.2 μM filtered |
| Endotoxin | ≤ 1.0 EU/mg |
| Purity | 99% |
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