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BioSIM anti-Human CD30 Antibody (Brentuximab Biosimilar), Research Grade

Catalog: SIM0101
Cost advantage to: SIM0073
Isotype: IgG1-kappa
Product Details Specifications Application References Related Products

Product Details

This non-therapeutic biosimilar shares the same variable regions as therapeutic Brentuximab (a humanized IgG1 mAb targeting CD30, a 120 kDa glycoprotein expressed in CD8+/CD4+ lymphocytes, eosinophils, etc., absent in peripheral blood, making it a therapeutic target) and is ideal for research. Brentuximab is part of BV ADC, delivering MMAE to CD30+ cancer cells in studies on HL, sALCL, PTCL, etc.
 

Specifications

Product Name BioSIM anti-Human CD30 Antibody (Brentuximab Biosimilar), Research Grade
Size 1mg/5mg
Isotype IgG1-kappa
Target CD30
Other Names SGN-35, cAC10-Val-Cit-MMAE, CAS: 914088-09-8, 2088770-90-3
CAS 914088-09-8, 2088770-90-3
Reactivity Human
Host Species Chimeric
Background This non-therapeutic biosimilar shares the same variable regions as therapeutic Brentuximab (a humanized IgG1 mAb targeting CD30, a 120 kDa glycoprotein expressed in CD8+/CD4+ lymphocytes, eosinophils, etc., absent in peripheral blood, making it a therapeutic target) and is ideal for research. Brentuximab is part of BV ADC, delivering MMAE to CD30+ cancer cells in studies on HL, sALCL, PTCL, etc.
Applications ELISA, FACS, Functional assay, Research in vivo
Purification Protein A/G
Storage To ensure appropriate storage, Please avoid repeated freeze thaw cycles. Keep the product at 4°C for short-term needs (1–2 weeks); Store at -20°C for up to 12 months.  For long-term storage, store at -80°C.
Shipping 2-8°C with blue ice
Concentration Lot specific, generally ≥ 5.0 mg/ml
Shelf Life 12 months from the date of receipt if stored as recommended
Formulation PBS, pH 7.4, contains no stabilizers or preservatives
Sterility 0.2 μM filtered
Endotoxin ≤ 1.0 EU/mg
Purity 99%

Application References

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