Discover our extensive collection of research-grade antibodies,
rigorously validated for in vivo applications.
Precisely identify antibody-specific signals using matched isotype controls optimised for in vivo experimentation.
BiosimilarsInvestigate biological therapeutic mechanisms with cost-effective, research-grade biosimilar antibodies.
This non-therapeutic biosimilar, with Tocilizumab’s variable regions, is ideal for research. It reacts with human IL-6R (CD126, an 80 kDa type I cytokine receptor in the immunoglobulin superfamily) expressed on activated T/B lymphocytes, monocytes, hepatocytes, and plasma cells. IL-6Rα binds IL-6 but needs gp130 for signal transduction; the complex influences immune/inflammatory responses and more. Tocilizumab binds soluble/membrane-bound IL-6R, blocking IL-6 binding.
| Product Name | BioSIM anti-Human IL-6R Antibody (Tocilizumab Biosimilar), Research Grade |
| Size | 1mg/5mg |
| Isotype | IgG1 |
| Target | IL-6R |
| Other Names | Atlizumab, MRA, R-1569, RHPM-1, RO-4877533, CAS: 375823-41-9 |
| CAS | 375823-41-9 |
| Reactivity | Human |
| Host Species | Humanized |
| Background | This non-therapeutic biosimilar, with Tocilizumab’s variable regions, is ideal for research. It reacts with human IL-6R (CD126, an 80 kDa type I cytokine receptor in the immunoglobulin superfamily) expressed on activated T/B lymphocytes, monocytes, hepatocytes, and plasma cells. IL-6Rα binds IL-6 but needs gp130 for signal transduction; the complex influences immune/inflammatory responses and more. Tocilizumab binds soluble/membrane-bound IL-6R, blocking IL-6 binding. |
| Applications | ELISA, FACS, Functional assay, Research in vivo |
| Purification | Protein A/G |
| Storage | To ensure appropriate storage, Please avoid repeated freeze thaw cycles. Keep the product at 4°C for short-term needs (1–2 weeks); Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Shipping | 2-8°C with blue ice |
| Concentration | Lot specific, generally ≥ 5.0 mg/ml |
| Shelf Life | 12 months from the date of receipt if stored as recommended |
| Formulation | PBS, pH 7.4, contains no stabilizers or preservatives |
| Sterility | 0.2 μM filtered |
| Endotoxin | ≤ 1.0 EU/mg |
| Purity | 99% |
© 2021-2025 InvivoCrown Limited. All rights reserved.