Discover our extensive collection of research-grade antibodies,
rigorously validated for in vivo applications.
Precisely identify antibody-specific signals using matched isotype controls optimised for in vivo experimentation.
BiosimilarsInvestigate biological therapeutic mechanisms with cost-effective, research-grade biosimilar antibodies.
This biosimilar antibody shares variable regions with therapeutic Sacituzumab, ideal for research. Sacituzumab is a fully humanized IgG1κ mAb targeting human TROP-2 (cancer-linked). TROP-2, with ligands like claudin-1/7, upregulates cell signaling, is a trophoblastic stem cell marker, highly expressed in tumors (e.g., glioblastoma, breast cancer), and an immunotherapy target. Recent studies use its ADC (e.g., Sacituzumab Govitecan) in preclinical research.
| Product Name | BioSIM anti-Human TROP2 Antibody (Sacituzumab Biosimilar), Research Grade |
| Size | 1mg/5mg |
| Isotype | IgG1-kappa |
| Target | TROP2 |
| Other Names | IMMU-132, hRS7-SN-38, hRS7-SN-38-ADC, hRS7-[CL-SN-38], CAS: 1796566-95-4 |
| CAS | 1796566-95-4 |
| Reactivity | Human |
| Host Species | Humanized |
| Background | This biosimilar antibody shares variable regions with therapeutic Sacituzumab, ideal for research. Sacituzumab is a fully humanized IgG1κ mAb targeting human TROP-2 (cancer-linked). TROP-2, with ligands like claudin-1/7, upregulates cell signaling, is a trophoblastic stem cell marker, highly expressed in tumors (e.g., glioblastoma, breast cancer), and an immunotherapy target. Recent studies use its ADC (e.g., Sacituzumab Govitecan) in preclinical research. |
| Applications | ELISA, FACS, Functional assay, Research in vivo |
| Purification | Protein A/G |
| Storage | To ensure appropriate storage, Please avoid repeated freeze thaw cycles. Keep the product at 4°C for short-term needs (1–2 weeks); Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Shipping | 2-8°C with blue ice |
| Concentration | Lot specific, generally ≥ 5.0 mg/ml |
| Shelf Life | 12 months from the date of receipt if stored as recommended |
| Formulation | PBS, pH 7.4, contains no stabilizers or preservatives |
| Sterility | 0.2 μM filtered |
| Endotoxin | ≤ 1.0 EU/mg |
| Purity | 99% |
© 2021-2025 InvivoCrown Limited. All rights reserved.