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BiosimilarsInvestigate biological therapeutic mechanisms with cost-effective, research-grade biosimilar antibodies.
This non-therapeutic biosimilar uses Pertuzumab’s variable regions, ideal for research. It binds human HER2’s extracellular dimerization domain (HER2: 185 kDa transmembrane proto-oncoprotein, overexpressed in ~40% breast cancers, linked to poor prognosis). Pertuzumab treats HER2-positive metastatic breast cancer by inhibiting HER2 dimerization with other HER receptors, slowing tumor growth.
| Product Name | BioSIM anti-Human HER2 Antibody (Pertuzumab Biosimilar), Research Grade |
| Size | 1mg/5mg |
| Isotype | IgG1-kappa |
| Target | HER2 |
| Other Names | OMNITARG, rhuMAB2C4, CAS: 380610-27-5 |
| CAS | 380610-27-5 |
| Reactivity | Human |
| Host Species | Humanized |
| Background | This non-therapeutic biosimilar uses Pertuzumab’s variable regions, ideal for research. It binds human HER2’s extracellular dimerization domain (HER2: 185 kDa transmembrane proto-oncoprotein, overexpressed in ~40% breast cancers, linked to poor prognosis). Pertuzumab treats HER2-positive metastatic breast cancer by inhibiting HER2 dimerization with other HER receptors, slowing tumor growth. |
| Applications | ELISA, FACS, Functional assay, Research in vivo |
| Purification | Protein A/G |
| Storage | To ensure appropriate storage, Please avoid repeated freeze thaw cycles. Keep the product at 4°C for short-term needs (1–2 weeks); Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Shipping | 2-8°C with blue ice |
| Concentration | Lot specific, generally ≥ 5.0 mg/ml |
| Shelf Life | 12 months from the date of receipt if stored as recommended |
| Formulation | PBS, pH 7.4, contains no stabilizers or preservatives |
| Sterility | 0.2 μM filtered |
| Endotoxin | ≤ 1.0 EU/mg |
| Purity | 99% |
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