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BioSIM anti-Human CD20 Antibody (Ofatumumab Biosimilar), Research Grade

Catalog: SIM0067
Cost advantage to: SIM0089
Isotype: IgG1-kappa
Product Details Specifications Application References Related Products

Product Details

This non-therapeutic biosimilar shares the same variable regions as therapeutic Ofatumumab, ideal for research. Ofatumumab, a fully human IgG1 monoclonal antibody, targets CD20 (a B cell surface antigen present from pre-B to mature B cells, not plasma cells). By binding CD20’s unique membrane-proximal epitope, it induces B cell depletion via CDC and ADCC, suiting studies on B cell-mediated diseases, CD20 biology, and B cell depletion mechanisms in autoimmune disease and cancer.
 

Specifications

Product Name BioSIM anti-Human CD20 Antibody (Ofatumumab Biosimilar), Research Grade
Size 1mg/5mg
Isotype IgG1-kappa
Target CD20
Other Names HuMax-CD20-, CAS: 679818-59-8
CAS 679818-59-8
Reactivity Human
Host Species Human
Background This non-therapeutic biosimilar shares the same variable regions as therapeutic Ofatumumab, ideal for research. Ofatumumab, a fully human IgG1 monoclonal antibody, targets CD20 (a B cell surface antigen present from pre-B to mature B cells, not plasma cells). By binding CD20’s unique membrane-proximal epitope, it induces B cell depletion via CDC and ADCC, suiting studies on B cell-mediated diseases, CD20 biology, and B cell depletion mechanisms in autoimmune disease and cancer.
Applications ELISA, FACS, Functional assay, Research in vivo
Purification Protein A/G
Storage To ensure appropriate storage, Please avoid repeated freeze thaw cycles. Keep the product at 4°C for short-term needs (1–2 weeks); Store at -20°C for up to 12 months.  For long-term storage, store at -80°C.
Shipping 2-8°C with blue ice
Concentration Lot specific, generally ≥ 5.0 mg/ml
Shelf Life 12 months from the date of receipt if stored as recommended
Formulation PBS, pH 7.4, contains no stabilizers or preservatives
Sterility 0.2 μM filtered
Endotoxin ≤ 1.0 EU/mg
Purity 99%

Application References

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