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This non-therapeutic Polatuzumab biosimilar, with the same variable regions as the therapeutic antibody, is ideal for research. It targets CD79b (a key BCR complex component regulating B cell function, expressed in malignant B cells like DLBCL but not plasma/non-B cells). Unconjugated (no cytotoxic MMAE), it lets study of CD79b binding/function without toxicity, suiting flow cytometry, B cell studies, preclinical modeling and ADC development.
| Product Name | BioSIM anti-Human CD79B Antibody (Polatuzumab Biosimilar), Research Grade |
| Size | 1mg/5mg |
| Isotype | IgG1-kappa |
| Target | CD79B |
| Other Names | ACD79B-VCMMAE, DCDS4501A, FCU2711, RO5541077-000, polatuzumabvedotin-piiq, CAS: 1313206-42-6 |
| CAS | 2279068-37-8 |
| Reactivity | Human |
| Host Species | Humanized |
| Background | This non-therapeutic Polatuzumab biosimilar, with the same variable regions as the therapeutic antibody, is ideal for research. It targets CD79b (a key BCR complex component regulating B cell function, expressed in malignant B cells like DLBCL but not plasma/non-B cells). Unconjugated (no cytotoxic MMAE), it lets study of CD79b binding/function without toxicity, suiting flow cytometry, B cell studies, preclinical modeling and ADC development. |
| Applications | ELISA, FACS, Functional assay, Research in vivo |
| Purification | Protein A/G |
| Storage | To ensure appropriate storage, Please avoid repeated freeze thaw cycles. Keep the product at 4°C for short-term needs (1–2 weeks); Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Shipping | 2-8°C with blue ice |
| Concentration | Lot specific, generally ≥ 5.0 mg/ml |
| Shelf Life | 12 months from the date of receipt if stored as recommended |
| Formulation | PBS, pH 7.4, contains no stabilizers or preservatives |
| Sterility | 0.2 μM filtered |
| Endotoxin | ≤ 1.0 EU/mg |
| Purity | 99% |
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