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BiosimilarsInvestigate biological therapeutic mechanisms with cost-effective, research-grade biosimilar antibodies.
This non-therapeutic biosimilar uses Omalizumab’s variable regions, ideal for research. It reacts with free human IgE (blood/interstitial fluid) and membrane-bound IgE on IgE-expressing B cells. It doesn’t bind IgE already bound to FcεRI (mast cells, basophils, dendritic cells) or trigger histamine release from IgE-sensitized mast cells, binding an epitope near FcεRI’s binding site.
| Product Name | BioSIM anti-Human IgE/IGHE Antibody (Omalizumab Biosimilar), Research Grade |
| Size | 1mg/5mg |
| Isotype | IgG1-kappa |
| Target | IgE/IGHE |
| Other Names | IGE25, olizumab, pSVIE26, rhuMab-E25, CAS: 242138-07-4, MaE11 |
| CAS | 242138-07-4 |
| Reactivity | Human |
| Host Species | Humanized |
| Background | This non-therapeutic biosimilar uses Omalizumab’s variable regions, ideal for research. It reacts with free human IgE (blood/interstitial fluid) and membrane-bound IgE on IgE-expressing B cells. It doesn’t bind IgE already bound to FcεRI (mast cells, basophils, dendritic cells) or trigger histamine release from IgE-sensitized mast cells, binding an epitope near FcεRI’s binding site. |
| Applications | ELISA, FACS, Functional assay, Research in vivo |
| Purification | Protein A/G |
| Storage | To ensure appropriate storage, Please avoid repeated freeze thaw cycles. Keep the product at 4°C for short-term needs (1–2 weeks); Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Shipping | 2-8°C with blue ice |
| Concentration | Lot specific, generally ≥ 5.0 mg/ml |
| Shelf Life | 12 months from the date of receipt if stored as recommended |
| Formulation | PBS, pH 7.4, contains no stabilizers or preservatives |
| Sterility | 0.2 μM filtered |
| Endotoxin | ≤ 1.0 EU/mg |
| Purity | 99% |
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