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BioSIM anti-Human IL-17A Antibody (Secukinumab Biosimilar), Research Grade

Catalog: SIM0029
Cost advantage to: SIM0013
Isotype: IgG1-kappa
Product Details Specifications Application References Related Products

Product Details

This non-therapeutic Secukinumab biosimilar, sharing the same variable regions as the therapeutic version, is ideal for research. It reacts with human IL-17A (15-20 kDa, expressed by Th17, γδ T, iNKT, NK, LTi cells, neutrophils, intestinal Paneth cells). IL-17A has pleiotropic immunoregulatory/inflammatory effects (aids anti-microbial/chronic inflammation, drives autoimmune diseases like RA, asthma); Secukinumab neutralizes it.
 

Specifications

Product Name BioSIM anti-Human IL-17A Antibody (Secukinumab Biosimilar), Research Grade
Size 1mg/5mg
Isotype IgG1-kappa
Target IL-17A
Other Names AIN457, CAS: 1229022-83-6
CAS 1229022-83-6
Reactivity Human
Host Species Human
Background This non-therapeutic Secukinumab biosimilar, sharing the same variable regions as the therapeutic version, is ideal for research. It reacts with human IL-17A (15-20 kDa, expressed by Th17, γδ T, iNKT, NK, LTi cells, neutrophils, intestinal Paneth cells). IL-17A has pleiotropic immunoregulatory/inflammatory effects (aids anti-microbial/chronic inflammation, drives autoimmune diseases like RA, asthma); Secukinumab neutralizes it.
Applications ELISA, FACS, Functional assay, Research in vivo
Purification Protein A/G
Storage To ensure appropriate storage, Please avoid repeated freeze thaw cycles. Keep the product at 4°C for short-term needs (1–2 weeks); Store at -20°C for up to 12 months.  For long-term storage, store at -80°C.
Shipping 2-8°C with blue ice
Concentration Lot specific, generally ≥ 5.0 mg/ml
Shelf Life 12 months from the date of receipt if stored as recommended
Formulation PBS, pH 7.4, contains no stabilizers or preservatives
Sterility 0.2 μM filtered
Endotoxin ≤ 1.0 EU/mg
Purity 99%

Application References

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