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BioSIM anti-Human IL-2Ra/CD25 Antibody (Daclizumab Biosimilar), Research Grade

Catalog: SIM0024
Cost advantage to: SIM0035
Isotype: IgG1-kappa
Product Details Specifications Application References Related Products

Product Details

This non-therapeutic Daclizumab biosimilar (same variable regions, ideal for research) binds the Tac epitope on human IL-2Rα (CD25, Ly-43, p55). IL-2Rα, on activated immune cells, aids lymphocyte functions; with IL-2Rβ/γ, it binds IL-2 tightly. It blocks IL-2 binding (no T-cell depletion) and inhibits IL-2-dependent T-cell functions.
 

Specifications

Product Name BioSIM anti-Human IL-2Ra/CD25 Antibody (Daclizumab Biosimilar), Research Grade
Size 1mg/5mg
Isotype IgG1-kappa
Target IL-2Ra/CD25
Other Names BIIB019, DACHYP, CAS: 152923-56-3
CAS 152923-56-3
Reactivity Human
Host Species Humanized
Background This non-therapeutic Daclizumab biosimilar (same variable regions, ideal for research) binds the Tac epitope on human IL-2Rα (CD25, Ly-43, p55). IL-2Rα, on activated immune cells, aids lymphocyte functions; with IL-2Rβ/γ, it binds IL-2 tightly. It blocks IL-2 binding (no T-cell depletion) and inhibits IL-2-dependent T-cell functions.
Applications ELISA, FACS, Functional assay, Research in vivo
Purification Protein A/G
Storage To ensure appropriate storage, Please avoid repeated freeze thaw cycles. Keep the product at 4°C for short-term needs (1–2 weeks); Store at -20°C for up to 12 months.  For long-term storage, store at -80°C.
Shipping 2-8°C with blue ice
Concentration Lot specific, generally ≥ 5.0 mg/ml
Shelf Life 12 months from the date of receipt if stored as recommended
Formulation PBS, pH 7.4, contains no stabilizers or preservatives
Sterility 0.2 μM filtered
Endotoxin ≤ 1.0 EU/mg
Purity 99%

Application References

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