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This non-therapeutic Adalimumab biosimilar, sharing the therapeutic antibody’s variable regions, fits research use. It binds human TNFα—a proinflammatory cytokine signaling via TNFR1/TNFR2. TNFα, mainly from macrophages (also monocytes, NK cells), regulates immunity/cell functions; its dysregulation links to autoimmune diseases and cancer. The biosimilar blocks TNFα-receptor interaction, reducing autoimmune-related inflammation.
| Product Name | BioSIM anti-Human TNF-α Antibody (Adalimumab Biosimilar), Research Grade |
| Size | 1mg/5mg |
| Isotype | IgG1-kappa |
| Target | TNF-α |
| Other Names | ABP501, D2E7, Adalimumab, AdalimumabBeta, CAS: 331731-18-1 |
| CAS | 331731-18-1 |
| Reactivity | Human |
| Host Species | Human |
| Background | This non-therapeutic Adalimumab biosimilar, sharing the therapeutic antibody’s variable regions, fits research use. It binds human TNFα—a proinflammatory cytokine signaling via TNFR1/TNFR2. TNFα, mainly from macrophages (also monocytes, NK cells), regulates immunity/cell functions; its dysregulation links to autoimmune diseases and cancer. The biosimilar blocks TNFα-receptor interaction, reducing autoimmune-related inflammation. |
| Applications | ELISA, FACS, Functional assay, Research in vivo |
| Purification | Protein A/G |
| Storage | To ensure appropriate storage, Please avoid repeated freeze thaw cycles. Keep the product at 4°C for short-term needs (1–2 weeks); Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Shipping | 2-8°C with blue ice |
| Concentration | Lot specific, generally ≥ 5.0 mg/ml |
| Shelf Life | 12 months from the date of receipt if stored as recommended |
| Formulation | PBS, pH 7.4, contains no stabilizers or preservatives |
| Sterility | 0.2 μM filtered |
| Endotoxin | ≤ 1.0 EU/mg |
| Purity | 99% |
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