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BioSIM anti-Human EGFR Antibody (Panitumumab Biosimilar), Research Grade

Catalog: SIM0019
Cost advantage to: SIM0050
Isotype: IgG2-kappa
Product Details Specifications Application References Related Products

Product Details

This biosimilar antibody has the same variable regions as therapeutic Panitumumab, ideal for research. Panitumumab, a fully humanized IgG2κ mAb, binds wild-type human EGFR and its mutant EGFRvIII. EGFR mediates cell signaling; Panitumumab blocks its activation, inhibiting cell growth, inducing apoptosis. In vitro/in vivo studies show it arrests cell cycle and suppresses tumor growth.
 

Specifications

Product Name BioSIM anti-Human EGFR Antibody (Panitumumab Biosimilar), Research Grade
Size 1mg/5mg
Isotype IgG2-kappa
Target EGFR
Other Names ABX-EGF, E7.6.3, CAS: 339177-26-3
CAS 339177-26-3
Reactivity Human
Host Species Human
Background This biosimilar antibody has the same variable regions as therapeutic Panitumumab, ideal for research. Panitumumab, a fully humanized IgG2κ mAb, binds wild-type human EGFR and its mutant EGFRvIII. EGFR mediates cell signaling; Panitumumab blocks its activation, inhibiting cell growth, inducing apoptosis. In vitro/in vivo studies show it arrests cell cycle and suppresses tumor growth.
Applications ELISA, FACS, Functional assay, Research in vivo
Purification Protein A/G
Storage To ensure appropriate storage, Please avoid repeated freeze thaw cycles. Keep the product at 4°C for short-term needs (1–2 weeks); Store at -20°C for up to 12 months.  For long-term storage, store at -80°C.
Shipping 2-8°C with blue ice
Concentration Lot specific, generally ≥ 5.0 mg/ml
Shelf Life 12 months from the date of receipt if stored as recommended
Formulation PBS, pH 7.4, contains no stabilizers or preservatives
Sterility 0.2 μM filtered
Endotoxin ≤ 1.0 EU/mg
Purity 99%

Application References

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